Hello Kaushik,
The Web Dispatcher trace that was provided shows it sending a request to the backend system "PWQ".
However, the PWQ system definition is commented at the profile that was attached,
Thus, for sure that was not the profile used while the trace was captured.
In addition, there is no "500" error being returned by the Web Dispatcher (or the issue was not simulated using HTTP).
Without the correct profile used during the issue simulation, and without the trace capturing the issue, we would not be able to assist you.
Regards,
Isaías